Classified in categories
Digestive tract * Haemorrhoids and rectal diseases * OTC, Prescription drugsPROCTO-GLYVENOL suppositories 10
| Application form | rectal preparations (suppositories, ointments and creams) |
| Indication group | antihemorrhoids |
| Manufacturer | Herbacos Recordati s.r.o., Pardubice, Czech Republic, www.recordati.cz |
| Active substance | Tribenosidum 400 mg, Lidocaini hydrochloridum monohydricum 40 mg |
| minimum amount for dispatch | Procto-Glvenol : Tribenoside, a synthetic compound belonging to the group of glucofuranosides, and lidocaine, local anaesthetic (contained in both forms of Procto-Glyvenol), bring a rapid relief of unpleasant symptoms connected with haemorrhoids (pain, tingling, pricking, feeling of tight skin) that are usually caused by a secondary inflammation of the anorectal area. A healing effect of Procto-Glyvenol in patients with haemorrhoids is guaranteed due to its specific activity - first, owing to its ability to decrease permeability of walls of the smallest vessels and to increase the vessel wall tension - and second, owing to its local anti-inflammatory effect and owing to its action against various substances which originate in the inflammatory tissue and which take a joint effect in development of inflammation and pain. The lidocaine component helps to relieve pain quickly. As Procto-Glyvenol is aimed to reach a local effect, it is desirable for the absorption of the active substance tribenoside into the body to be as lowest as possible. Approximately 2-20% of tribenoside will be absorbed by the skin from the cream, from one suppository it is 20-27% of the dose. After absorption tribenoside is subjected to an intensive metabolism in the body and the substances created in this way are excreted into urine. Lidokaine is absorbed in a very small amount and does affect neither the central nervous system, nor the heart function. |
Summary of product characteristics  SHOW | Information on a drug is available on the official website: Medicines.org.uk or EMEA : European Medicines Agency |
| SUKL | PROCTO-GLYVENOL rct sup 10 - 0180555 |
